FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques

HIV

PLOS Pathogens: Suppression of human and simian immunodeficiency virus replication with the CCR5-specific antibody Leronlimab in two species

HIV

Leronlimab (PRO 140) in vitro activity against 4-class drug resistant HIV-1 from heavily treatment experienced subjects

HIV

Frontiers in Immunology: CCR5 Receptor Occupancy Analysis Reveals Increased Peripheral Blood CCR5+CD4+ T Cells Following Treatment With the Anti-CCR5 Antibody Leronlimab

HIV

Nature Communications: Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission

HIV

Antimicrobial Agents and Chemotherapy: Phase 2a Study of the CCR5 Monoclonal Antibody PRO 140 Administered Intravenously to HIV-Infected Adults

HIV